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Orphan Black - Season 1 Finale - Speculation

Thanks to The Spoiler Fairy

In the preview video for episode 1.10 of Orphan Black, Cosima is seen coughing up blood. Based on the original casting notice for the part of Sarah/Beth/Karen/Alison/Cosima, we'll find out that Cosima has cystic fibrosis. From her research Cosima discovers that the clones have "degraded" DNA, which affects their lifespan. Something else that may be significant: We haven't met a clone named "Karen," so she may be one of the nine clones that we haven't seen yet. There was no detailed information about Karen in the casting notice.