UPDATE: Moffat has also teased that River WILL be returning next season.
Steven Moffat has announced at the Press Screening today that the Ponds will leave in Season 7 and that a new companion will join the Doctor on his travels. Amy and Rory will be in quite a few of the episodes it seems, but their departure will be "heartbreaking".
As yet no-one has been cast as the new companion.
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