Wilfred - Comic-Con Summary

The episode we saw, "Pride," was about Elijah Wood's Ryan being forced to swallow his, um, pride, after getting into a car accident with the always-awesome Jane Kaczmerak (Malcolm in the Middle). The show will be seen later on this season.

Executive Producer David Zuckerman mentioned not trusting his dog as much ever since beginning work on the show.

Jason Gann came up with the idea for Wilfred after hearing about a friend, who had a dog that was causing problems with his lady. Gann began talking in the voice of the dog and they eventually shot a short film.

Source: Full article @ UGO