The Walking Dead - Season 2 - Sarah Wayne Callies Interview

We watched Sunday's upcoming episode -- it's a big one for Lori. We really see more of her strength coming out. Is she taking the reins from Rick?
In some ways, yeah, I think she is. This is a woman who's never considered herself any kind of leader or any kind of thinker, but she is seeing the ways in which the burdens of leadership are affecting her husband and he's kind of going down a rabbit hole. And I think part of her says, "Okay, I'll do it. I'll take on as much responsibility as possible to protect you" and at another level she's a mom and this is her kid and she is going to save him if she has to fight every walker in Atlanta with her teeth.

Are we going to see Lori get into any close calls with walkers? She's always had someone around to help.
I think it's inevitable that at a certain point in the story everyone is going to end up in an inadvertent dark corner with no one to defend them and they're going to have to figure it out. Lori's made some really smart decisions about keeping herself and her son safe, but as the pressures of what happens to Carl and what's happens to Sophia mounts it clouds her decisions and she stops making decisions that are quite as smart.
Source: Full interview @ Zap2it